B-hEPO mice

    C57BL/6N-Epotm1(EPO)Bcgen/Bcgen • 112458

    B-hEPO mice

    Product nameB-hEPO mice
    Catalog number112458
    Strain nameC57BL/6N-Epotm1(EPO)Bcgen/Bcgen
    Strain backgroundC57BL/6N
    NCBI gene ID (Human)
    AliasesEP; DBAL; ECYT5; MVCD2

    在此页面上

    • Targeting strategy
    • Phenotypic analysis

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      发表文章

        Targeting strategy

        Gene targeting strategy for B-hEPO mice. The exons 1-5 of mouse Epo gene that encodes the full-length protein were replaced by human EPO exons 1-5 in B-hEPO mice.

        Protein expression analysis
        Strain specific EPO expression analysis in homozygous B-hEPO mice by ELISA. Serum were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hEPO mice (H/H) and analyzed by ELISA with species-specific EPO ELISA kit. Mouse EPO was detectable in wild-type mice (A). Human EPO was exclusively detectable in homozygous B-hEPO mice but not in wild-type mice (B).* 1 ng/mL=21.2 miu/L
        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hEPO mice] (Cat# 112458) was purchased from Biocytogen.
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